Human Growth Hormone Peptides

Human Growth Hormone Peptides

Human growth hormone peptides — supplementation designed to help increase energy and reverse the visible signs of aging

Human growth hormone (hGH) is a natural hormone produced by your pituitary gland. As you age, the level of hGH in your body declines. By the time you are middle age, your body’s production of hGH is reduced by 85 percent. As hGH declines, you may experience increased body fat, wrinkly skin, hair loss, lack of energy, low libido, and decreased muscle mass. But when hGH production is again increased, every part of the body begins to respond positively: You may burn fat for energy and “turn back time,” which may slow the aging process.

Side effects

Unfortunately, taking human growth hormones can be risky, since known side effects include cancer, carpal tunnel syndrome, abnormal bone and tissue growth, breast tissue enlargement in men, heart problems, and increased risk of diabetes. HGH peptides, small proteins made of amino acids, have proven to be safer because they stimulate the body’s natural production of hGH.

Sermorelin peptide therapy uses a special blend of amino acids that, when injected into the fatty layer of tissue just below the skin, stimulates the pituitary gland to produce and secrete hGH. Sermorelin therapy is natural, safe, and effective, and it eliminates the risks associated with hGH supplementation.

hGH peptide therapy benefits

Benefits of human growth hormone (hGH) peptide therapy may:

  • Stimulate your metabolism to burn fat
  • Increase energy levels
  • Improve oxygen and blood flow
  • Increase sex drive
  • Promote healthy skin, hair, and nail growth
  • Increase growth of lean muscle and lean body mass
  • Improve endurance and performance levels
  • Improve REM sleep quality, mental clarity, and mood
  • Increase bone and mineral density
  • Accelerate healing and injury repair
  • Enhance immune-system function
  • Regenerate nerve tissue

Many adults over the age of 35 can benefit from increased hGH levels not just for restoring youth, but also for improving their overall health and well-being. Whether you’re athletic or not, an on-the-go mom or a busy executive, Sermorelin therapy can help you maintain a healthy weight, sleep better, and have more energy.

Possible patient benefits over time

  • Week 1: Quality of sleep
  • Week 2: Recovery from workouts
  • Week 4: Mental clarity
  • Week 6: Skin elasticity
  • Week 8: Body composition

As with all of Equilibrium’s programs, our Anti-Aging hGH Peptide Program is customized to each client’s specific needs and includes personalized data about what’s going on inside your body. Contact us for a free consultation to learn how our peptide program can help you burn fat and feel younger!

What is Sermorelin?

Sermorelin is a form of growth hormone-releasing factor (GRF) that contains the first 29 amino acids. (GRF produced in the brain contains 44 amino acids.)

Sermorelin is a prescription drug injected into the fatty layer of tissue under the skin. It stimulates the pituitary gland to produce increased amounts of growth hormone, which causes the liver to increase production of Insulin-Like Growth Factor-1 (IGF-1).

Sermorelin therapy has been specifically approved for medical use to increase growth hormone levels in children deficient in growth hormone production. Using it to increase growth hormone and IGF-1 levels in adults is an off-label use.

What are the benefits of Sermorelin therapy?

The increased amount of IGF-1 in the bloodstream as a result of Sermorelin therapy boosts metabolism and the growth of new cells. This can increase lean muscle mass, reduce body fat, increase bone density, enhance the immune system, and strengthen the heart as well as other organs.


Is Sermorelin therapy the same as hGH therapy?

No. Sermorelin is a small peptide that contains only 29 amino acids; hGH (human growth hormone) is a much larger molecule that contains 191 amino acids.

Is Sermorelin therapy the same as hGH releasers?

No. Over-the-counter hGH releasers are usually the amino acids L-arginine, L-glutamine, L-ornithine, glycine, and L-dopa, as well as such substances as ornithine alpha-ketoglutarate and the herbs macuna pruriens and tribulus terrestris. Although high doses of these compounds sometimes do cause the pituitary gland to release hGH, the effects are intermittent and unreliable. In addition, high doses of amino acids can create kidney problems, presenting a risk to adults who regularly use such products.

In contrast, Sermorelin works like naturally occurring growth hormone-releasing hormone. It also has an excellent safety profile with few side effects.

Why should someone consider Sermorelin therapy as an hGH therapy alternative?

Sermorelin therapy offers all the benefits of hGH therapy but without the overdosing concerns associated with hGH therapy. Patients using Sermorelin will never produce more growth hormone than their bodies can safely process, as the increased volume of hGH is produced by the patient’s own pituitary gland and amounts are regulated by the body’s endocrine system.

Because Sermorelin stimulates the pituitary gland, it prevents the hormone decline that occurs during aging, preserving not only youthful anatomy but also youthful physiology. In addition, Sermorelin’s off-label use is not prohibited by federal law.

Is Sermorelin injected like hGH?

Currently, the only method for effectively administering Sermorelin is by injection into the fatty layer of tissue just under the skin. However, because the molecule is much smaller than hGH, it may someday be possible to administer it successfully using a nasal spray. This method is currently being tested.

Are the dosages of hGH and Sermorelin comparable?

Although the molecules work at different sites in the body (hGH at the liver and Sermorelin at the pituitary), the amount of material needed to raise IGF-1 is approximately the same. hGH is generally prescribed in daily doses of 1-2 international units (IU), while Sermorelin is typically prescribed in doses of 100-300 micrograms per day.

How do the costs of hGH therapy and Sermorelin therapy compare?

Sermorelin therapy is significantly less expensive than hGH therapy. A vial of hGH usually lasts about 12-14 days. In contrast, one multidose vial of Sermorelin lasts 15-30 days.

What causes hGH to lose potency?

Loss of hGH potency after about six months of continuous use is not unusual.

Normally, hGH levels increase and decrease many times throughout the day, which means your body’s tissue receptors have time to “rest.” However, when hGH is injected, blood levels of the hormone are elevated to unnaturally high values for several hours each day, and production of IGF-1 also increases. This unnatural exposure to hGH and IGF-1 causes tissue receptors to “down regulate” in an attempt to prevent overstimulation, resulting in decreased potency.

Does Sermorelin lose potency?

No. In Sermorelin therapy, hGH is released from the pituitary in episodes, which allows the tissue receptors time to rest.

Does Sermorelin therapy have any non-endocrine benefits?

Yes. Many reports in peer-reviewed medical and scientific journals show that Sermorelin promotes non-REM slow-wave sleep.

How is Sermorelin therapy administered?

Sermorelin is administered by injection once daily before bedtime. The time of injection is important because Sermorelin facilitates the nocturnal release of hGH. Dosage is based on each patient’s needs.

What are the possible side effects of Sermorelin therapy?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome: facial flushing; headache; nausea; pain, redness, or swelling at injection site; paleness; strange taste in mouth; vomiting.

Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

Are there restrictions to taking Sermorelin?

Some medical conditions may interact with Sermorelin acetate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • You are pregnant, planning to become pregnant, or are breast-feeding
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • You have allergies to medicines, foods, or other substances
  • You have a head or brain injury or disease

Some medicines may interact with Sermorelin acetate. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cyclooxygenase inhibitors (e.g., aspirin, indomethacin)
  • Glucocorticoids (e.g., prednisone)
  • Insulin
  • Medicines that lower thyroid levels (e.g., propylthiouracil)
  • Muscarinic antagonists (e.g., atropine),
  • Somatostatin-containing medicines or medicines that release somatostatin (e.g., clonidine, levodopa).

If you are taking any of these medications, the effectiveness of Sermorelin acetate may be decreased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sermorelin acetate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.